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Pediatric cancers (general) research papers

Papers tagged to Pediatric cancers (general). Adjust filters if you want a narrower scope.

3 papersSorted by most recent
DoBSeqWF: a framework for sensitive detection of individual genetic variation in pooled sequencing data.
NAR genomics and bioinformatics • 2026-03-01 • DOI: 10.1093/nargab/lqag021
Peer-reviewedImpact 77

Topics

Treatment, Diagnosis, Screening / Early detection, Epidemiology

Modality

Imaging

Study type

Observational

Abstract

Population screening for rare genetic diseases has the potential to increase early diagnosis and treatment, but the high cost of next-generation sequencing limits widespread implementation. Double-batched sequencing (DoBSeq) is a cost-effective method that uses two-dimensional overlapping pool sequencing to enable individual-level rare variant detection.…

Authors

Mads Cort Nielsen, Christian Munch Hagen, Ulrik Kristoffer Stoltze, Thomas van Overeem Hansen +8

AI-generated summary

DoBSeqWF: a framework for sensitive detection of individual genetic variation in pooled sequencing data. reports: Population screening for rare genetic diseases has the potential to increase early diagnosis and treatment, but the high cost of next-generation sequencing limits widespread implementation. Double-batched sequencing (DoBSeq) is a cost-effective method that uses two-dimensional overlapping pool sequencing to enable individual-level rare variant detection. However, the resulting high-depth, complex data require a specialized workflow for efficient, sensitive, and reproducible analysis.

This summary may be inaccurate. Verify with the primary paper.

Primary source: PubMed.

"I felt so seen": Perspectives on age-appropriate, needs-based survivorship care among young adult survivors of childhood, adolescent, or young adult cancers (CAYA).
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer • 2026-02-17 • DOI: 10.1007/s00520-026-10369-8
Peer-reviewedImpact 71

Topics

Screening / Early detection

Modality

Imaging

Study type

Not listed

Abstract

Survivors of childhood, adolescent, and young adult cancers (CAYA) experience unique survivorship needs that are often unaddressed. We characterized young adult CAYA survivors' perspectives on the acceptability and utility of a novel model for routinely identifying and addressing their needs in survivorship care. Our…

Authors

Andrea C Betts, Ally Jacobs, Nathan Overholt, Janae Russell +7

AI-generated summary

"I felt so seen": Perspectives on age-appropriate, needs-based survivorship care among young adult survivors of childhood, adolescent, or young adult cancers (CAYA). reports: Survivors of childhood, adolescent, and young adult cancers (CAYA) experience unique survivorship needs that are often unaddressed. We characterized young adult CAYA survivors' perspectives on the acceptability and utility of a novel model for routinely identifying and addressing their needs in survivorship care. Our onco-primary care program implemented routine needs-based care using age-appropriate needs and distress screening at survivorship visits.

This summary may be inaccurate. Verify with the primary paper.

Primary source: PubMed.

Peer-reviewedImpact 71

Topics

Treatment, Biology / Mechanism, Outcomes / Survival, Side effects / Toxicity, Prevention / Risk, Epidemiology

Modality

Immunotherapy, Targeted therapy, Radiation, Imaging

Study type

Observational, Review / Meta-analysis

Abstract

Oncolytic virotherapy employs genetically modified viruses to selectively lyse tumor cells while activating antitumor immune responses. In pediatric oncology, where outcomes for high-grade gliomas and refractory solid tumors remain poor, oncolytic viruses represent a promising therapeutic strategy. A systematic review was conducted in accordance…

Authors

Amani S BinSharhan, AlJouhrah M AlAbdullah, Shouq F Alabdullatif, Yara Y Aboushark +4

AI-generated summary

A Decade of Oncolytic Virotherapy in Pediatric Cancers: A Systematic Review of Safety, Immune Awakening, and Emerging Efficacy. reports: Oncolytic virotherapy employs genetically modified viruses to selectively lyse tumor cells while activating antitumor immune responses. In pediatric oncology, where outcomes for high-grade gliomas and refractory solid tumors remain poor, oncolytic viruses represent a promising therapeutic strategy. A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines, including searches of PubMed, Embase, Scopus, Web of Science, and ClinicalTrials.gov for studies published between 2015 and 2025 that evaluated oncolytic virotherapy in patients aged 18 years or younger.

This summary may be inaccurate. Verify with the primary paper.

Primary source: PubMed.