Biomarker hub

FGFR2 fusion

FGFR2 fusions are common in cholangiocarcinoma and often guide targeted therapy trials.

Trials mentioning fgfr2View all trials

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

RECRUITING · Phase not listed

A Study Evaluating Bemarituzumab in Solid Tumors With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

COMPLETED · Phase not listed

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

RECRUITING · Phase not listed

Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations

NOT_YET_RECRUITING · Phase not listed

MP0317 in Combination With Chemoimmunotherapy in First Line Treatment for Patients With Advanced Biliary Tract Carcinoma

RECRUITING · Phase not listed

Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements

ACTIVE_NOT_RECRUITING · Phase not listed

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RECRUITING · Phase not listed

Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors

TERMINATED · Phase not listed

Futibatinib in Patients With Specific FGFR Aberrations

TERMINATED · Phase not listed

A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

TERMINATED · Phase not listed

Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)

COMPLETED · Phase not listed

Efficacy and Safety of 3D185 Monotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma

NOT_YET_RECRUITING · Phase not listed

A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

TERMINATED · Phase not listed

Pemigatinib After Curative Local Therapy in Advanced iCCA With FGFR2 Fusion/Rearrangements

TERMINATED · Phase not listed

Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements

TERMINATED · Phase not listed

Expanded Access Study of TAS-120 in Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements

APPROVED_FOR_MARKETING · Phase not listed

A Phase 2 Clinical Study of ABSK061 and ABSK043

RECRUITING · Phase not listed

Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinoma

NOT_YET_RECRUITING · Phase not listed

Study to Evaluate the Efficacy and Safety of TT-00420 (Tinengotinib) in Cholangiocarcinoma

COMPLETED · Phase not listed

Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma

RECRUITING · Phase not listed

Papers mentioning fgfr2View all papers