Biomarker hub
TMB-High
Trials and papers mentioning TMB-High.
Trials mentioning tmbView all trials
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
SUSPENDED · Phase not listed
Exploration of Sintilimab + Bevacizumab + AG Chemotherapy as First-Line Treatment for Unresectable Advanced/Metastatic Cholangiocarcinoma
NOT_YET_RECRUITING · Phase not listed
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
RECRUITING · Phase not listed
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
RECRUITING · Phase not listed
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype
ACTIVE_NOT_RECRUITING · Phase not listed
A Phase II Clinical Study of Aipalolitovorelizumab (QL1706) Combined With Fruquintinib in the Treatment of Immunodominant pMMR/MSS Metastatic Colorectal Cancer That Has Failed Second-line or Above Treatment
NOT_YET_RECRUITING · Phase not listed
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RECRUITING · Phase not listed
Study of Acquired Resistance to Alkylator Chemotherapy in Endocrine Neoplasms
RECRUITING · Phase not listed
A Beta-only IL-2 ImmunoTherapY Study
RECRUITING · Phase not listed
A Prospective, Open-label, Exploratory Basket Trial to Evaluate the Efficacy and Safety of Sintilimab Combined With Pyrotinib ± Chemotherapy in Patients With Advanced Digestive System Tumors
NOT_YET_RECRUITING · Phase not listed
AIO-BNHO Comprehensive Clinico-genomics Database Network - AIO-BNHO CONNECT
RECRUITING · Phase not listed
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients
ACTIVE_NOT_RECRUITING · Phase not listed
Combination of Spartalizumab, mDCF and Radiotherapy in Patients With Metastatic Squamous Cell Anal Carcinoma
RECRUITING · Phase not listed
Combination of CAR-DC Vaccine and ICIs in Malignant Tumors
RECRUITING · Phase not listed
Papers mentioning tmbView all papers
Expert consensus on the detection and clinical application of tumor mutational burden.
Cancer biology & medicine · 2/17/2026
Nanoheterojunction-Based Self-Powered Biosensor Integrated with Smartphones for Early Cancer Detection.
Advanced healthcare materials · 2/17/2026
Tumors with mutations in chromatin regulators are associated with higher mutational burden and improved response to checkpoint immunotherapy
genetic and genomic medicine · 2/19/2025