Biomarker hub
MSI-High
Trials and papers mentioning MSI-High.
Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
RECRUITING · Phase not listed
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
RECRUITING · Phase not listed
A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
RECRUITING · Phase not listed
Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)
RECRUITING · Phase not listed
Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis
ACTIVE_NOT_RECRUITING · Phase not listed
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
ACTIVE_NOT_RECRUITING · Phase not listed
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
RECRUITING · Phase not listed
PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma
RECRUITING · Phase not listed
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
RECRUITING · Phase not listed
Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer
NOT_YET_RECRUITING · Phase not listed
A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer
RECRUITING · Phase not listed
Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
RECRUITING · Phase not listed
A First-in-human, Dose Escalation and Dose Expansion Study of SAR445877 in Adult Participants With Advanced Solid Tumors
RECRUITING · Phase not listed
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
SUSPENDED · Phase not listed
GYNORYLAQ™-VLINIVAL™: Ψ-Guided Personalized Neoantigen Peptide Vaccine for High-Risk Endometrial Cancer
ENROLLING_BY_INVITATION · Phase not listed
AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
ACTIVE_NOT_RECRUITING · Phase not listed
How Epigenetic Changes in hMLH1 Connect Lab Research With Diagnosis in Gastric Cancer
RECRUITING · Phase not listed
Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer
RECRUITING · Phase not listed
A Study to Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive
ACTIVE_NOT_RECRUITING · Phase not listed
A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.
NOT_YET_RECRUITING · Phase not listed
Discovery and Preclinical Evaluations of Potent, Selective, and Allosteric Covalent WRN Inhibitors with Improved PK Properties.
ACS medicinal chemistry letters · 2/12/2026
The dysregulation of the immune microenvironment during endometrial intraepithelial neoplasia serves as a marker of endometrial carcinogenesis.
Frontiers in immunology · 1/1/2026